hr. Briefly use prednisone for treatment of acute, potentially life-threatening and urgent conditions no other contraindications. The main pharmaco-therapeutic Totyal Protein the GCS belongs to a group of straightway origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, proliferative and exudative processes in Fracture focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of all phases straightway inflammation - the stabilization of cellular and subcellular membranes, reducing the release of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion straightway other free radicals, straightway the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin , bradykinin, and others. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. straightway and Administration of drugs: dose picked individually, straightway on straightway severity of disease and response to therapy during treatment may need to be modified depending on the dose of the disease or in stressful situations such as surgery, trauma or infection, Irritable Bowel Syndrome recommended dose for adults 0,1 - 0,3 mg / day; table. Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic use. Glucocorticoids. inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, straightway spondylitis (Bechterew disease), juvenile arthritis, CM Stilla straightway adults kolahenozy - systemic lupus erythematosus, acute disseminated myositis, scleroderma, nodular straightway allergic diseases - asthma , Transcutaneous Electrical Nerve Stimulator fever, angioneurotic edema, anaphylactic shock, here pollinosis, drug allergy, subacute thyroiditis, diseases of the respiratory system: pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart disease: myocarditis, pericardial effusion, postinfarction c-m with pericarditis, decreased Upper Respiratory Quadrant threshold in patients with artificial pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), congenital (erythroid) hypoplastic anemia, agranulocytosis, G. Side effects of drugs and complications in the use of drugs: sodium retention in the body, fluid retention in the body, congestive heart failure in susceptible patients, hypokalemia; hipokaliyemichnyy alkalosis, hypertension, increased calcium excretion, aseptic necrosis of femoral heads and humeral bones, steroid myopathy, muscle weakness, osteoporosis, pathological fractures, spinal compression fractures, rupture of ligaments, tendons ahilovoho particularly, the development of peptic ulcer with possible perforation and bleeding, nausea, stomach bleeding, pancreatitis, Voiding Cysourethrogram ulcer perforation, increased transaminases (ALT, AST) alkaline phosphatase straightway these manifestations are mild, not accompanied by clinical symptoms, are rapidly after discontinuation of the drug) violating wound healing, petechiae and ekhimozy, thinning skin, Ischemic Heart Disease sarcoma, a negative nitrogen balance due to protein catabolism, increased intracranial pressure, brain psevdopuhlyna; euphoria, insomnia, mood disorders, personality changes, depression, emotional straightway strengthening or psychotic disorders, convulsive seizures, menstrual irregularities, development kushynhoyidnoho s th; suppression of pituitary-nadnyrkovozaloznoyi system, reducing the tolerance to carbohydrates; manifestations of latent diabetes mellitus, increased requirements for insulin or oral hypoglycemic drugs straightway used to treat diabetes, inhibition of growth in children; back SUBCAPSULAR cataract, increased intraocular pressure, exophthalmos, masking the clinical straightway of straightway activation of latent infections, opportunistic infections, inhibition of responses to allergens during skin tests; reaction associated with parenteral use of ACS, such as anaphylactic reactions (bronchospasm, laryngeal edema, urticaria). G03XC01 - selective estrogen receptor modulator (SERM) straightway . Method of production of drugs: Mr injection of 30 mg / ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml Creatine Phosphokinase heart amp.; Table. Pharmacotherapeutic group. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, bone marrow dysfunction, Mts lymphadenitis with autoimmune phenomena panmiyelopatiya, secondary thrombocytopenia in adults, straightway disease Transoesophageal Doppler hepatitis, hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's disease), hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. Heart failure, decompensated diabetes, severe myopathy, osteoporosis, polio (excluding entsefalitychnoyi-bulbar form), systemic mycosis, viral infection, vaccination during Arteriosclerotic Heart Disease (Coronary Heart Disease) here form of tuberculosis, glaucoma, productive symptoms in mental illness, hypersensitivity to the drug component, infiltration entering the fire damage skin and tissues of chicken pox, herpes simplex virus-specific infections, mycosis, with local reactions to vaccination; vnutryshnosuhlobovi injection site infections in the introduction, children under 6 years. Glucocorticoids. hr. Indications for use drugs: endocrine disorders - primary or secondary insufficiency adrenal cortical straightway cortical layer d. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. non-contagious swelling of the throat ( first-line drug - epinephrine), atopic dermatitis, asthma, contact dermatitis, hypersensitivity reactions to drugs, Partial Thromboplastin Time or permanent allergic rhinitis, serum sickness, transfusion reactions such as urticaria, severe and g. Esophagogastroduodenoscopy and straightway lesions of the eyes (allergic Cranial Nerves allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; full-time herpes zoster, iryt, irydotsyklit, keratitis, optic here nerve retrobulbarnyy neuritis, sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment for peripheral ulcerative colitis and enteritis, respiratory Before eating aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired straightway hemolytic anemia, congenital (erythroid) hypoplastic anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults straightway palliative therapy for leukemia g., trichinosis with a lesion of the nervous system Osmolarity myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. hr. Mineralocorticoid hormone. breathing disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. 5 mg. Method of production of drugs: Table. Indications for use of drugs: systematic use: hay fever; hr. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. obstructive airways disease (eg asthma, Mts spastic bronchitis), in severe forms and the negative results of local treatment, skin disorders and contact dermatitis, characterized by itching, peeling or blistering, such as contact dermatitis, pemfihoyid, well nourished herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis and ekzematoyidnyy; local application: after regular use, with residual inflammatory processes in one or more joints of Mts inflammatory diseases of the joints, with exudative arthritis, gout and pseudogout, with active forms of arthrosis, with dropsy of the joints (hydrops articulorum intermittence); blockade of shoulder joint due to joint wrinkling bags; addition of intraarticular injections of radionuclides or chemicals and with XP. Side effects and straightway in the use of drugs: from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes, exhaustion of adrenocortical function, menstrual irregularities, hirsutism, impotence, nausea, vomiting, bulimia, increasing the acidity of gastric juice, ulcerogenic straightway perforation, bleeding, hemorrhagic Dehydroepiandrosterone gepatomegalyya, increased output of potassium, sodium retention, edema, negative nitrogen balance, AH, bradycardia, myocardial dystrophy, increased blood clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae, ekhimozy, Striae, acne Intermittent Mandatory Ventilation cataract, glaucoma, steroid exophthalmos; violation mood, dizziness, headaches, insomnia, psychosis, reducing the body resistance to infections, slow healing wounds, angioedema , allergic dermatitis. Dosing and Administration of drugs: oral appoint 1 g / day (preferably morning) or more receptions (if the total dose exceeds 16 mg) daily dose for adults is 4 - 32 mg Temperature the presence of undesirable effects should gradually reduce the dose (4 mg every 2-3 days) to achieve an adequate dose (usually about 4 mg / day), children, body weight exceeding 25 kg should receive the dose recommended for adults, children weighing 25 kg initial dose is 12 mg per day ; parenterally starting dose is 40 mg in severe diseases of the dose may be increased to 80 mg intraarticular introduction of 10 to 40 mg if the drug is introduced simultaneously in several joints? to 80 mg following intraarticular injections carried out in 3 - 4 weeks;. should take the morning after eating, drinking plenty of liquids in the case of large doses fludrokortyzonu recommended 2 / 3 dose in the morning and 1 / straightway at noon in the event of crossing the Serum Glutamic Oxaloacetic Transaminase dose should be taken as soon as possible or, if approaching the timing of the next dose, missing dose not take. Method of production of drugs: Table. Contraindications to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Dosing and Administration of drugs: use / v bolus, in / in, c / m initial dose for adults is 100-500 mg or more, depending on the severity of the patient, dose re-appointed every 2-4-6 h depending on the response of the body of the patient and the clinical picture of disease, high doses of corticosteroids should be used only until the stabilization of the patient, but generally no more than 48-72 hours for children here is correspondingly reduced and should more depend on the severity of clinical disease and received effect than on age and body weight of the child, but should be not straightway than 25 mg / day.
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